Go West on Alligator Alley to Interstate I-75 North. Follow I-75 North
to Exit 21, Daniels Parkway. Follow directions from I-75.
WEST PALM BEACH
Go West on Route 441 to Route 27 then to Route 80. Take interstate I-75 South to Exit 21, Daniels Parkway. Go West on Daniels and follow directions from I-75.
Take Interstate I-75 South to Exit 21, Daniels Parkway. Go West on Daniels and follow directions from I-75.
Take Interstate I-4 West to Interstate I-75 South. Follow I-75 South to Exit 21 Daniels Parkway. Go West on Daniels and follow directions from I-75.
FT. MYERS AIRPORT/I-75
Go West on Daniels Parkway, Summerlin Road. (When you cross U.S. 41 Daniels changes its name to Cypress Lake.) Turn Left onto Summerlin Road to Sanibel. When you come over the Sanibel Causeway ($3.00 toll) turn Right at the first stop sign onto Periwinkle Way. Follow Periwinkle to the 4-way stop about 3 miles. Turn Right at Tarpon Bay Road. Follow to 4-way stop. Turn Left onto Sanibel-Captiva (San-Cap) Road. Follow San-Cap for 7 miles and you will cross a small bridge which connects Sanibel and Captiva. "Tween Waters Inn is 2 miles after bridge on the right.